Background: Perineal rupture occurs almost in all the first labor and not infrequently in the next labor. Complex perineal wounds are at risk for non-healing and infection.
Objective: This study aims to determine the effect of bird’s nest extract on perineal wound healing on rattus norvegicus.
Methods: This was a randomized posttest only group design conducted in October 2016 at Animal Laboratory Unit of Diponegoro University, Semarang, Indonesia. There were 30 samples recruited in this study, divided into three groups: 1) the control group (with povidone iodine 10% solution), 2) the first treatment group with a bird’s nest 50% cream, and 3) the second treatment group with a bird’s nest 70% cream. The Redness, Edema, Ecchymosis, Discharge, Approximation (REEDA) scale was used. Data were analyzed using descriptive statistics, frequency distribution, and one-way ANOVA.
Results: There were statistically significant mean differences between the three groups with p-value 0.000 (< 0.05). The time of the wound healing was 5-6 days for povidone iodine 10% group, 4-5 days for bird’s nest 50% group, and 3 days for bird’s nest 70% group. The degree of perineal wound density in the bird’s nest 70% group (0.37) was also better than the bird’s nest 50% group (0.13) and povidone iodine 10% group (0.02).
Conclusion: Bird’s nest has a significant effect on wound healing process. Findings indicated that the bird’s nest 70% extract was very effective to accelerate wound healing than bird’s nest 50% extract and povidone iodine 10%.
Copyright (c) 2017 Herlina Ofiwijayanti, Syarief Thaufik Hidayat, Nur Khafidhoh
This work is licensed under a Creative Commons Attribution 4.0 International License.
Article MetricsAbstract views: 731 | PDF views: 296
Marshall JE, Raynor MD. Myles' textbook for midwives: Philadelphia: Elsevier Health Sciences; 2014.
Bahiyatun SP. Buku ajar asuhan kebidanan nifas normal [Teaching book of midwifery care for normal postpartum]. Jakarta: EGC; 2009.
Manuaba IAC. Buku ajar patologi obstetri [Teaching book of obstetric patology]. Jakarta: EGC; 2009.
Adhiyanti Y, Pitriani R, Damayanti IP. Panduan lengkap ketrampilan dasar kebidanan [Complete guideline of basic skills of midwifery]. Yogyakarta: Deepublish; 2014.
Rejeki S. Faktor-faktor yang berpengaruh pada penyembuhan luka perineum ibu pasca persalinan di Puskesmas Brangsong dan Kaliwungu Kabupaten Kendal [Factors influencing perineal wound healing in postpartum mothers at Public Health Centers of Brangson and Kaliwungu Kabupaten Kendal]. Paper presented at Seminar Nasional & Internasional, Semarang: Universitas Muhammadiyah Semarang; 2010.
Sukmono RJ. Mengatasi aneka penyakit dengan terapi herbal [Dealing with all diseases with herbal therapy]. Jakarta: Agromedia Pustaka; 2009.
Harmanto N, Subroto MA. Pilih jamu dan herbal tanpa efek samping [Choosing herbs without side effects]. Jakarta: Elex Media Komputindo; 2007.
Bird Nest facts and Knowledge. 2016; http://www.authenticbirdnest.com/index.php?option=com_content&task=view&id=27&Itemid=1. Accessed January 17, 2017.
Günter CI, Machens HG. New strategies in clinical care of skin wound healing. European Surgical Research. 2012;49(1):16-23.
Marcone MF. Characterization of the edible bird’s nest the “Caviar of the East”. Food Research International. 2005;38(10):1125-1134.
Abidin FZ, Hui CK, Luan NS, Ramli ESM, Hun LT, Ghafar NA. Effects of edible bird's nest (EBN) on cultured rabbit corneal keratocytes. BMC Complementary and Alternative Medicine. 2011;11(1):94.
Potter PA, Perry AG. Buku ajar fundamental keperawatan: Konsep, proses, dan praktik [Teaching book in basic nursing: Concept, process, and practice]. Jakarta: EGC; 2005.
Davidson N. REEDA: Evaluating postpartum healing. Journal of Nurse-Midwifery. 1974;19(2):6-8.
Alvarenga MB, Francisco AA, Oliveira SMJVd, Silva FMBd, Shimoda GT, Damiani LP. Episiotomy healing assessment: Redness, Oedema, Ecchymosis, Discharge, Approximation (REEDA) scale reliability. Revista Latino-Americana de Enfermagem. 2015;23(1):162-168.
Niall M, Ryan GB, O'Brien BM. The effect of epidermal growth factor on wound healing in mice. Journal of Surgical Research. 1982;33(2):164-169.
Kong YC, Keung WM, Yip TT, Ko KM, Tsao SW, Ng MH. Evidence that epidermal growth factor is present in swiftlet's (Collocalia) nest. Comparative Biochemistry and Physiology Part B: Comparative Biochemistry. 1987;87(2):221-226.
Lee SH, Jeong SK, Ahn SK. An Update of the defensive barrier function of skin. Yonsei Medical Journal. 2006;47(3):293-306.
Tracy LE, Minasian RA, Caterson EJ. Extracellular matrix and dermal fibroblast function in the healing wound. Advances in Wound Care. 2016;5(3):119-136.