Fe-fortified tempe

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Wulandhari, A., Supriyana, S., Bahiyatun, B., Hadisaputro, S., & Mashoedi, I. D. (2017). EFFECT OF FE-FORTIFIED TEMPE ON HEMATOLOGIC STATUS IN PREGNANT MOTHERS WITH ANEMIA. Belitung Nursing Journal, 3(4), 370–375. https://doi.org/10.33546/bnj.157
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Accepted for publication: 2017-08-31
Peer reviewed: Yes

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Background: The prevalence of anemia among pregnant mothers is still high in Indonesia. Fe-fortified tempe is a traditional soy product originating from Indonesia considered able to increase hematologic status.

Objective: This study aims to determine the effect of Fe-fortified tempe on hemoglobin, hematocrit, and erythrocyte levels in pregnant women with anemia.

Methods: This was a true-experimental study with randomized pretest and posttest control group design, conducted on November - December 2016 in Bandarharjo Health Center, Semarang, Indonesia. Sixty-eight respondents were selected using simple random sampling, with 34 respondents were randomly assigned to each group. Blood examination was performed in each respondent. Mean, percentage, and frequency distribution of respondents were described. Paired t test and independent t test with α = 0.05 were performed to analyze the data.

Result: Findings showed that hemoglobin, hematocrit, and erythrocyte levels before and after intervention in the treatment group showed p-value 0.000 (< 0.05), which means there was a significant effect of Fe-fortified on the increase of hemoglobin, hematocrit, and erythrocyte levels.

Conclusion: There was an increase in hemoglobin, hematocrit, and erythrocyte levels after given Fe-fortified tempe for 10 consecutive days. It is suggested that pregnant women can consume Fe-fortified tempe.


Supporting Agencies

Magister Applied Midwifery, Poltekkes Kemenkes Semarang, Indonesia


Copyright (c) 2017 Anggraini Wulandhari, Supriyana, Bahiyatun, Soeharyo Hadisaputro, Imam Djamaluddin Mashoedi

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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Goonewardene M, Shehata M, Hamad A. Anaemia in pregnancy. Best Practice & Research Clinical Obstetrics & Gynaecology. 2012;26(1):3-24.

Banhidy F, Acs N, Puho EH, Czeizel AE. Iron deficiency anemia: pregnancy outcomes with or without iron supplementation. Nutrition. 2011;27(1):65-72.

Bendich A. Preventive nutrition: the comprehensive guide for health professionals. Berlin, Germany: Springer Science & Business Media; 2013.

Scholl TO, Hediger ML, Fischer RL, Shearer JW. Anemia vs iron deficiency: Increased risk of preterm delivery in a prospective study. The American Journal of Clinical Nutrition. 1992;55(5):985-988.

Ministry of Health of Indonesia. Pedoman operasional penanggulangan anemia gizi di Indonesia [Operational guideline of anemia management in Indonesia]. Jakarta: Direktorat Pembinaan Kesehatan Masyarakat. Ministry of Health of Indonesia; 1998.

Rukiyah AY, Yulianti L. Asuhan kebidanan IV (patologi kebidanan) [Midwifery care IV (midwifery pathology)]. Jakarta: Trans Info Media; 2010.

Sudargo T, Nisa FZ, Helmiyati S, Kusuma RJ, Arjuna T, Septiana RD. Tempeh with iron fortification to overcome iron deficiency anemia. Pakistan Journal of Nutrition. 2013;12(9):815-820.

Salmiah. Influence of consume cake base on tempe formula by fortified fe for child under five years old anemia of Fe. Makssar, Indonesia: Universitas Hasanuddin; 2014.

Khoigani MG, Goli S, HasanZadeh A. The relationship of hemoglobin and hematocrit in the first and second half of pregnancy with pregnancy outcome. Iranian Journal of Nursing and Midwifery Research. 2012;17(2 Suppl1):S165.

Billett HH. Hemoglobin and hematocrit. In: Walker HK, Hall WD, Hurst JW, eds. Clinical methodsL The history, physical and laboratory examinations. 3rd ed. Boston: Butterworths; 1990.

Tabrizi FM, Barjasteh S. Maternal hemoglobin levels during pregnancy and their association with birth weight of neonates. Iranian Journal of Pediatric Hematology and Oncology. 2015;5(4):211.

Abbassi-Ghanavati M, Greer LG, Cunningham FG. Pregnancy and laboratory studies: A reference table for clinicians. Obstetrics & Gynecology. 2009;114(6):1326-1331.

Martorell R, Ascencio M, Tacsan L, et al. Effectiveness evaluation of the food fortification program of Costa Rica: Impact on anemia prevalence and hemoglobin concentrations in women and children. The American Journal of Clinical Nutrition. 2015;101(1):210-217.

Gropper SS, Smith JL. Advanced nutrition and human metabolism: Boston: Cengage Learning; 2012.

Sloan NL, Jordan E, Winikoff B. Effects of iron supplementation on maternal hematologic status in pregnancy. American Journal of Public Health. 2002;92(2):288-293.

UNICEF/WHO. Preventing iron deficiency in women and children: technical consensus on key issues. New York: UNICEF/WHO; 1998.

Rosso P. Nutrition and metabolism in pregnancy: mother and fetus. Oxford: Oxford University Press; 1990.

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