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This issue focuses on the theme of "Advancing Quality Care and Patient Safety." It presents a diverse collection of articles that offer valuable insights and contribute to our understanding of emerging trends and challenges in the healthcare field. The articles explore various important topics, such as the cultural appropriateness of educational interventions for pain management in patients with cancer, the impact of organizational support on the work commitment of healthcare professionals, the development and validation of assessment tools to measure pain self-efficacy in patients with cancer, intergenerational perspectives on health and health research among different ethnic groups, and the opportunities and challenges in lifelong learning and professional development for nurses in a cancer hospital. The collective findings presented in these articles serve as a valuable resource for healthcare professionals, researchers, and policymakers dedicated to advancing the frontiers of quality care and patient safety.